Brendan Raftery, Founder & Principal.

I'm Brendan Raftery, founder of Advanced Research and Concepts (ARC), an independent research and product strategy practice.

I'm a builder. Everything I've done in my career comes from the same drive: making things that didn't exist before.

I started my career in manufacturing at Millennium Pharmaceuticals (now Takeda), learning how drugs actually get made at scale and under real operational pressure. I managed contract manufacturers for drug product and for packaging and labeling, worked with distribution centers and contract QC testing labs, wrote batch records, ran manufacturing investigations and change controls, and worked on two drug launches. That left me with a question I couldn't let go of: how do we decide what to make in the first place? It pulled me into product strategy. Digital health was just emerging as a serious field, and it gave me a way to make the move. I started with a secondment into a digital health role at Millennium, then joined Pfizer full-time to work on a patient support program for people living with metastatic breast cancer.

From Pfizer I moved into consulting at Pilot44, where I worked with large organizations across multiple industries on innovation and product development. The work surfaced a distinction I kept seeing organizations get wrong. Research and development aren't the same activity. Research is exploratory and unscheduled. It can't be run to a predetermined timeline or be evaluated on milestone completion. Development is goal-directed work with a specific product at the end of it, subject to the real pressures of the marketplace.

The organizations that struggle most with innovation typically have a robust research function and almost no development capability. They can generate interesting ideas and run pilots. What they can't do is make the sustained, disciplined transition from a promising direction into a commercialized product. This is what most people mean when they talk about innovation theater: activity that looks like R&D but never produces anything that ships. Pharma is one of the few industries that still understands this distinction and builds around it. I started my career there, and that shaped how I think about strategy work.

After Pilot44, I joined Memorial Sloan Kettering Cancer Center, where I led digital health product strategy and was part of the team that launched MSK Direct Enhanced Virtual Services, a mobile app for cancer patients whose employers are MSK Direct partners. I also conducted research that became the basis for two peer-reviewed publications in JCO Oncology Practice.

I founded ARC to work on the gaps I'd spent a career watching. Most strategy work starts with a conclusion and builds backward toward evidence. Most organizations that want to innovate lack the development rigor to turn ideas into products that reach the market. I built ARC to close both gaps, starting with research and following the evidence.

I also use AI throughout my own work, which lets a one-person practice research and build with the reach of a small team. I'm based in Bayonne, New Jersey.

Start with better questions.

In a world where answers are increasingly easy to find, the most valuable skill is knowing which questions to ask, especially the ones that surface what you don't know you don't know. Good research starts with question design. Data collection comes after.

People over ideas.

Even the best ideas hit obstacles on the way to market. What determines whether something survives contact with reality is less the idea itself and more the people carrying it. People with both the skills and the behavioral inclinations to see hard things through are the most reliable investment available. Ideas are abundant. Those people aren't.

Emergence over authority.

The best outcomes in creative and strategic work rarely come from the top down. They surface when the right conditions exist. Leaders who function as gardeners tend to produce more durable work. They focus on what the team needs to succeed, then let the best ideas rise.

The antidisciplinary advantage.

The hardest problems don't respect disciplinary boundaries. The people best equipped to work on them tend to be those who've moved across fields rather than deepened into one. I have a degree from a pharmacy school and one from a design school. On paper, that's an odd combination. That path wasn't accidental, and it isn't finished. I think holding contradictions, and working across disciplines, is essential to creative work.

Career

  • Millennium Pharmaceuticals (now Takeda): Manufacturing and Supply Chain Management
  • Pfizer: Digital Health Product Strategy & Development
  • Pilot44: Innovation Consulting
  • Memorial Sloan Kettering Cancer Center: Digital Health Product Strategy & Development

Certifications

  • Lean Six Sigma Green Belt (Takeda)

Products launched

  • ENTYVIO: FDA-approved GI therapy (Takeda)
  • NINLARO: FDA-approved cancer therapy (Takeda Oncology)
  • Amba Wellness Coach: patient support program for metastatic breast cancer patients on IBRANCE (Pfizer)
  • PowerHeal: bioelectric bandage from Vomaris Innovations, developed with P&G Ventures (at Pilot44)
  • MSK Direct Enhanced Virtual Services: mobile app for cancer patients (Memorial Sloan Kettering)
  • Lens AI: enterprise software product, sold by Thought Industries

Teaching

  • Parsons School of Design: Graduate studio and design research courses (part-time faculty)

Guest lectures

  • UCSF Internal Medicine Residency Program
  • UC Berkeley Haas School of Business MBA Program
  • Icahn School of Medicine at Mount Sinai Preventive Medicine Residency Program
  • University of Miami Miller School of Medicine MD/MPH Program
  • Massachusetts College of Pharmacy and Health Sciences PharmD Program

Publications

  • “Impact of a remote second opinion program on changes in recommended treatment plans for patients with cancer across the US.” JCO Oncology Practice.
  • “What is the cost impact of second opinions in oncology? A retrospective review.” JCO Oncology Practice.

If you're working on something ambitious, email me a short note about what you're building, shipping or running and the help you're looking for.

Email Brendan